--- vault_clearance: SAFE halo: classification: OPERATIONAL confidence: HIGH front: "Clinical Translation — Specific Cancer Cases" custodian: "Jixiang Leng" created: 2026-04-09 updated: 2026-04-19 wing: UNASSESSED containment: "Active patient support. Specific case deliverables only. No PII in public surfaces." --- # 27_Project_WingsAboveMorning > *"We said we would cure cancer. This is how we keep that promise for one specific man first."* **Project triad:** [BOUNTY_BOARD.md](BOUNTY_BOARD.md) · [WORLDLINE.md](WORLDLINE.md) · [FORM.md](FORM.md) · [BOOK.md](BOOK.md) · vault [§6 workflow](../README.md#6-workflow-applies-across-all-projects) · **Ring #27 of 33** — [`_VAULT_STATE.md`](../_VAULT_STATE.md). ## Purpose — Scope Narrowed 2026-04-17 **This project is the clinical-deliverable project for specific cancer cases.** It produces WORD deliverables (per `WORD_DELIVERABLE_PROTOCOL.md`) that go directly to patients, families, and treating clinicians. General cancer biology, splice theory, independence axis theory, coupling tensor method papers — **these have moved to their appropriate research projects**: - **General cancer mechanisms** → [28_Project_RedFromTheGrave/theory_cancer_general/](../28_Project_RedFromTheGrave/theory_cancer_general/) - **Splice / STAFF / binary transcriptome** → [20_Project_MarathonLament/fused_from_27/](../20_Project_MarathonLament/fused_from_27/) - **Coupling tensor methodology (case-anchored)** → stays here; **(general)** copied to [22_Project_StarSight/fused_from_27/](../22_Project_StarSight/fused_from_27/) - **Plague atlas / pathogen detection tools** → [28_Project_RedFromTheGrave/tools/plague/](../28_Project_RedFromTheGrave/tools/plague/) - **Coherence-tensor tool source** → [22_Project_StarSight/tools/coherence/](../22_Project_StarSight/tools/coherence/) - **VM results from WI-38 lyso hunt, osiris/Sup35N, osiris/RodA** → [28_Project_RedFromTheGrave/vm_results/](../28_Project_RedFromTheGrave/vm_results/) and [28/osiris_validation/](../28_Project_RedFromTheGrave/osiris_validation/) - **VM results from ramuthra structural isoform atlas** → [20_Project_MarathonLament/vm_structural_atlas/](../20_Project_MarathonLament/vm_structural_atlas/) ## Active Cases ### Case 001 — Korean NSCLC (primary deliverable) **Status:** READY for family delivery. Oncology team review pending. **Deliverables:** - [deliverables/full_stack_korean_lung_cancer_case.word.md](deliverables/full_stack_korean_lung_cancer_case.word.md) — WORD deliverable (meta, delivery plan, evidence audit) - [Korean Lung Cancer/폐암_완전_안내서_FULL_GUIDE.md](Korean%20Lung%20Cancer/폐암_완전_안내서_FULL_GUIDE.md) — Korean-language master document (the artifact itself) - [HALO_THE_FULL_STACK.md](HALO_THE_FULL_STACK.md) — English-language evidence compilation - [HALO_OPERATOR_COUPLING_NSCLC.md](HALO_OPERATOR_COUPLING_NSCLC.md) — case-adjacent coupling tensor analysis (GSE131907, Korean NSCLC, 208k cells) - [Korean Lung Cancer/MASTER_ACTION_BRIEF_EN_KO.md](Korean%20Lung%20Cancer/MASTER_ACTION_BRIEF_EN_KO.md) — 72-hour bilingual checklist - [Korean Lung Cancer/case_state_live.json](Korean%20Lung%20Cancer/case_state_live.json) — case state tracker **Case supporting data:** - `vm_results/eye_genesis/` — NSCLC Zilionis STAFF outputs + tensor DBs + HUVEC D03 (NSCLC-relevant) - `companion_runtime/` — patient session projection engine - `Combined Emails/FIVE_LETTERS.md` — clinical correspondence drafts ## Structure After 2026-04-17 Reorg ``` 27_Project_WingsAboveMorning/ ├── README.md ← you are here ├── FORM.md — project form (scope-narrowed) ├── BOOK.md — bibliography for case work ├── BOUNTY_BOARD.md — case-scoped bounties │ ├── deliverables/ — ★ WORD deliverables ★ │ └── full_stack_korean_lung_cancer_case.word.md │ ├── Korean Lung Cancer/ — Case 001 case files │ ├── 폐암_완전_안내서_FULL_GUIDE.md ← THE artifact (Korean) │ ├── MASTER_ACTION_BRIEF_EN_KO.md — 72h checklist │ ├── Briefing 1/ — archival: initial multi-AI research │ ├── case_state_live.json — case tracker │ ├── ops_orchestrator.py — case ops automation │ └── Context.md — case background │ ├── HALO_THE_FULL_STACK.md — EN evidence compilation ├── HALO_OPERATOR_COUPLING_NSCLC.md — case-adjacent coupling ├── HALO_THE_INDEPENDENCE_AXIS.md — (stays for case cross-reference; copy in 22) │ ├── quantum_biology/ — Stefano package (Zenodo-ready) │ ├── release/ — shipping artifacts │ └── (note: candidate for promotion to own project later) │ ├── companion_runtime/ — patient session projection │ ├── Combined Emails/ — clinical correspondence │ ├── vm_results/ │ └── eye_genesis/ — NSCLC-relevant VM pulls │ ├── nsclc_zilionis_*.json — NSCLC STAFF outputs │ ├── p1_base4/frame.json — P1 HUVEC control │ ├── d03_tensor.json — HUVEC coupling tensor │ ├── atlas.db, sweep_atlas.db │ └── adult_normals.* — control tissue baselines │ ├── wings_above_morning.db — case-scoped storage ├── wings_database.json │ ├── _internal/ — drafts, sensitive └── _archive/ — superseded ``` ## Workflow — How Cases Move Through This Project ``` 1. NEW CASE RECEIVED │ ▼ 2. Case folder created: /Case_NNN_description/ Context.md captures all known facts case_state_live.json tracks unknowns (UNKNOWN = owner + deadline) │ ▼ 3. Research: general theory pulled from 28_RedFromTheGrave + 20_MarathonLament + 22_StarSight case-specific synthesis lives here │ ▼ 4. WORD deliverable authored: /deliverables/NAME.word.md Evidence audit, delivery plan, gap map │ ▼ 5. Patient-facing artifact written: localized-language master document │ ▼ 6. Delivery plan executed: family, oncologist, institutional case_state_live.json updated as information returns │ ▼ 7. WORD status: SHIPPED Follow-up cadence from Modeling Calendar section of WORD ``` ## Dependencies - **28_Project_RedFromTheGrave** — general cancer theory (Recycler framework, viral/imprinting, iron-macrophage axis, plague-atlas tool) - **20_Project_MarathonLament** — splice analysis engine (STAFF suite), structural isoform atlas - **22_Project_StarSight** — coupling tensor tooling (coherence package), spatial/ISM framework - **10_Project_DiscordIntoSymphony** — D01/D03/D04 HUVEC pipelines, orthodox monarch comparisons - **05_Project_LENG** — K_crit, Zeno/anti-Zeno theory (referenced for mechanism) - **08_Project_Astronomicon** — mailbox for external experiment proposals ## Bounty Board See [BOUNTY_BOARD.md](BOUNTY_BOARD.md) — case-scoped bounties only after 2026-04-17 reorg. ## What This Project Does NOT Contain (post-reorg) - ❌ General cancer biology HALOs (see 28) - ❌ Method papers on coupling tensor (see 22) - ❌ Splice/STAFF theory documents (see 20) - ❌ Pathogen/plague tool source (see 28/tools/plague) - ❌ WI-38 / osiris / structural atlas VM results (see 28, 20) ## What This Project DOES Contain - ✅ Specific case files and their supporting data - ✅ WORD deliverables — documents that ship TO patients/clinicians - ✅ Case-anchored coupling tensor analysis (Korean NSCLC only) - ✅ Companion runtime for patient session projection - ✅ Case correspondence - ✅ Case NSCLC-specific VM outputs (Zilionis STAFF, adult normals) --- *Updated 2026-04-17. Project narrowed from "clinical translation" broadly to "specific-case deliverables." The general research moved to its rightful homes. This project now does one thing: produce WORD deliverables that reach specific patients through specific delivery channels within specific timelines.*